Penicillamine-induced myasthenia gravis in progressive systemic sclerosis
نویسندگان
چکیده
منابع مشابه
D-Penicillamine induced myasthenia gravis.
Myasthenia gravis is a disorder of impaired neuromuscular transmission resulting in weakness and abnormal fatigability on exertion, improved by anti-acetyl cholinesterase drugs. A number of drugs are known to exacerbate myasthenia gravis or interfere with neuromuscular transmission. We report a case of D-penicillamine induced myasthenia gravis who developed ptosis, diplopia and easy fatigabilit...
متن کاملD-penicillamine Induced Myasthenia Gravis
Rheumatoid arthritis can be a very mutilating disease and, as a result, the likelihood of patients with rheumatoid arthritis requiring surgery and anaesthesia is increased. D-penicillamine (D-Pen) has been used in the treatment of rheumatoid arthritis and Wilson's disease since the early 1960s. Its true mode of action is unknown, but it appears to modify the immune response. Treatment with D-Pe...
متن کاملD-penicillamine induced myasthenia gravis. Its relevance for the anaesthetist.
The case of a 57-year-old woman with rheumatoid arthritis is presented to illustrate the rare occurrence of a myasthenic syndrome induced by D-penicillamine, which led to prolonged (5.25-h) postoperative apnoea necessitating artificial ventilation.
متن کاملOcular myasthenia gravis after D-penicillamine administration.
A 68-year-old black woman who was put on D-penicillamine therapy (250-500 mg per day, total dose 15 g) for rheumatoid arthritis developed ocular myasthenia gravis. Two weeks after she discontinued D-penicillamine her signs and symptoms cleared with no other treatment. Review of previous cases and possible immunological mechanisms are discussed.
متن کاملThymectomy in Patients with Myasthenia Gravis
A case of myasthenia gravis in a 15 years old girl is pre·sented. The disease was present for 5 years before thymectomy was performed. Indications for thymectomy, preoperative preparation, anesthetic and surgical management is -discussed.
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1980
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780230414